Stepwise mechanism for transcription fidelity
نویسندگان
چکیده
منابع مشابه
Efficient fidelity control by stepwise nucleotide selection in polymerase elongation
Polymerases select nucleotides before incorporating them for chemical synthesis during gene replication or transcription. How the selection proceeds stepwise efficiently to achieve sufficiently high fidelity and speed is essential for polymerase function. We examined step-by-step selections that have conformational transition rates tuned one at time in the polymerase elongation cycle, with a co...
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ژورنال
عنوان ژورنال: BMC Biology
سال: 2010
ISSN: 1741-7007
DOI: 10.1186/1741-7007-8-54